Bladder stones: A Technician's Perspective

Can you tell which cat has bladder stones?

In light of the numerous cases of bladder stones, crystals and inappropriate urination issues we have seen in the last month, I thought that I would share my own experience with bladder stones, in the hopes that others will take away the same lessons that I learned.

Marley

For over a decade, I shared my life with two lovely cats who were brother and sister. Mina, the sister, is still with me, but I lost Marley to lung cancer in 2013. Both cats came from a rescue group in East Lansing, siblings from a litter of hand-raised kittens whose mother had died when they were 10 days old. Both cats were fairly healthy during their younger years - Marley had a congenital cataract, Mina had some foul diarrhea. Marley had chronic skin allergies. Both cats went through a period of time when they had adverse vaccine reactions. Mina occasionally has bouts of bronchitis. Together, they
kept my hands full!

In September of 2009, I noticed that Marley had stopped squatting to urinate. I was annoyed by the habit, because he would stand in the litterbox and a big stream of urine would splatter out onto the floor in front of the box. I watched this go on for two weeks, because he didn't seem to be in pain - he didn't vocalize or strain when he urinated, he didn't seem to be going all that frequently - maybe 2-3 times daily. He didn't seem to be drinking more water than usual, and the urine wasn't bloody. I wondered if he had developed some arthritis in his hips - after all he was 9 years old at the time. I brought him in to work with me and after a thorough exam, we took hip x-rays. Dr. Brooks looked at the x-ray and said, "Well, his hips are fine, but he has bladder stones." I thought she was teasing me. I couldn't believe it. I looked for myself. Sure enough, there they were - 7 stones (I would share the x-ray, but it is in attic storage, now, and I don't like attics). A few weeks later, I scheduled him for surgery - I forget now, why I waited. It might have been a busy surgery schedule. I might have been saving up money. Anyway, it was a dumb idea to wait, because I was on pins and needles the whole time, worrying that he might become obstructed with a stone. This was a little silly, not because it wasn't possible, but because it takes weeks to months for stones to form, so he could have become obstructed at any time prior to his diagnosis, and I had not been worried, before. Worrying wasn't going to help him. Surgery was the only option.

Calcium oxalate stones

Surgery went smoothly, and 7 large stones (and two smaller stones that were not visible on the x-ray) were removed. We sent off the stones for analysis at the Minnesota Urolith Center and the report stated that they were 70% Calcium Oxalate Monohydrate and 30% Ammonium Acid Urate stones. After surgery, Marley didn't like using the clay litter we use here in the hospital, so he urinated bloody urine on the floor and towel until we switched him back to scoopable clumping litter. At home, he resumed urinating in the box normally, squatting like a good boy.

After that, he switched to a canned stone-prevention diet. Calcium oxalate stones do not dissolve with a dietary change, but they can be prevented from re-forming in many cases. Marley had bladder radiographs and urine rechecks every 6 months until 2012. I had a baby and went on maternity leave around the time that he was due for a recheck. In retrospect, I should have brought him in for a recheck early, but I was caught up in my own medical issues at the end of my pregnancy, and I figured a few months' delay was not that important.

But it was. In May of 2012, four months after the birth of my daughter, I was scheduling Marley for a

One large stone that required surgery to remove, and the many smaller stones we expressed.

repeat cystotomy. He had a bladder full of stones again. They were smaller, this time, but one stone was large enough that it could not be expressed. Marley recovered well from his second cystotomy and continued to do well until July 2013, when cancer took its toll.

Mina

Shortly after I lost Marley, his biological sister, Mina, started vomiting. She has had occasional bouts of acute vomiting, and was empirically
diagnosed with inflammatory bowel disease in 2005. In August 2012, she had a bout of vomiting that lasted about a week, and I brought her in for abdominal x-rays. At that time, she was having no issues urinating in the litterbox. She did not have any intestinal abnormalities, but there was a shadow in her bladder, which turned out to be a "puddle" of small stones. Fortunately, since she is a female, we were able to express all the small stones out of her bladder, and surgery was avoided. We sent in the stones to the Minnesota Urolith Center and they were 100% Calcium Oxalate stones. She has also been eating a crystal prevention diet and so far, she has had no further sign of stones on any of her followup xrays or urine samples.

If I had taken my own advice, many years ago, and fed canned food to my cats more often, I might

Sometimes, a lot of small stones look like one large stone

never have had to deal with this issue, as their urine might have been more dilute and less likely to form stones. I was very fortunate that neither of my cats decided to start urinating outside the litterbox due to discomfort - in fact, they are both very good examples of the fact that cats hide their problems from their owners. As a technician, I should be more attuned to signs and symptoms of illness, and I was unaware of the issues my own cats had. They are also a good testament to the importance of follow-up. Even if your cat seems fine after a treatment or procedure, it is important to follow-up on schedule. If I had brought Marley back 3 months earlier for a recheck, he might have been able to avoid the second cystotomy surgery. It may be that Mina will be one of the lucky few cats that never re-forms stones after a cystotomy, but you can be sure that I will continue to check her every 6 months!

Mina would rather nap than have a bladder recheck

What brings you here, today? The top 10 feline medical problems of 2014

Dr. Brooks examines a pediatric patient

If you have had a cat for any length of time, you have probably had to take him or her to the veterinary hospital for something other than an annual checkup at least once - anything from a bite wound from another cat to a broken toenail; stuffy noses, runny eyes or even (every cat owner's nightmare) choosing to urinate outside the litterbox.

Have you ever wondered, while sitting in the exam room waiting for the doctor, what other visitors to the hospital are bringing their cats in for? Veterinary Pet Insurance analyzes their claims each year, which can give us a good idea why most people are bringing their cats in to see the veterinarian. Last year, the top 10 reasons that cats visited the veteirnarian for a health issue were:

Cancerous cells typical of lymphoma

10) Lymphoma: a common and treatable form of cancer that affects one of the white blood cells (lymphocytes) and lymph nodes of a cat



9) Upper respiratory infection: Many young cats and kittens visit us because they are sneezing or have a runny nose or watery eyes. Some cats that have been affected by an upper respiratory infection as a young cat may have chronic but fairly manageable problems for the rest of their lives.

8) Inflammatory Bowel Disease: IBD is not a single disease but a complex group of symptoms and conditions that result from increased inflammation in the digestive tract. This condition can cause problems with digestion and absorption of nutrients, susceptibility to bacteria and viruses in the intestinal tract, vomiting, diarrhea, weight loss, poor hair coat, increased production of hairballs and more. For more information, you can read our blog article on IBD, here.

Drawing up insulin injections for a diabetic cat

7) Diabetes: Middle-aged to older cats, especially males and overweight cats are at higher risk for diabetes. As the obesity problem in US pets grows, the prevalence of diabetic pets has also increased. Almost 60% of cats are overweight in the United States, according to data collected by the Association for Pet Obesity Prevention (APOP) last year (2014).  For more information, you can read our blog article on diabetes, here.

6) Diarrhea or intestinal upset: Sometimes caused by intestinal parasites, diarrhea can be any stool that is soft or not well-formed, whether the cat can make it to the litterbox or not. Other causes of diarrhea may include diseases such as thyroid disease, IBD, or other problems, such as constipation (oddly enough), or eating a non-food item, such as a toy or ear plug.

5) Excessive thyroid hormone: Overactive thyroid glands produce more thyroid hormone than necessary, which can cause symptoms such as increased hunger and thirst, rapid heart rate, hyperactivity, vomiting, diarrhea and weight loss. For more information, you can read our blog article on hyperthyroid disease, here.

4) Vomiting/upset stomach: Vomiting may be related to an underlying medical issue such as thyroid disease, or may be caused by a food allergy, ingestion of a non-food item, a hairball that has become stuck in the digestive tract, heartworm disease, constipation or other problems.

3) Chronic kidney disease: A common problem in older cats is a progressive decrease in kidney function which can cause symptoms such as weight loss, vomiting or nausea, poor appetite.  For more information, you can read our blog article on Chronic kidney disease, here.

Annual oral exams help prevent serious dental disease

2) Periodontitis/dental disease: About 85% of cats over the age of 3 years have some amount of dental disease. Imagine the state you might be in if you didn't brush your teeth for three years or more! Most cats will need some level of dental care at some point in their lives. Just like people, a lot of a cat's dental health is related to genetics - enamel strength, tolerance of bacteria in the mouth, but regular dental checkups and cleanings can help prevent severe dental disease. For more information, you can read one of our blog articles about dental disease, here.

Making sure your cat likes the litterbox can help prevent urinary issues

1) Bladder or urinary tract disease: Just like VIP, the most common reason that we see cats for
medical care at Exclusively Cats is due to bladder or urinary problems - often because the cat has started to urinate outside the litterbox. There are many reasons that a cat might develop litterbox issues, many of which are medical and none of which are due to revenge or spite, despite what many people think or feel. As Dr. Deporter at Oakland Veterinary Referral Service is fond of saying, a cat's urine marking behavior is like leaving a sticky note with important information in a certain area. When we go by and clean up the urine without looking for the root of the problem, we are removing valuable cat information from the spot. This means the cat feels the need to re-post the sticky note - and they will continue to do so until the problem is addressed. The cat can read the "sticky note", other cats can read the "sticky note", but we humans cannot read the "sticky note" and need to use other means to figure out what the cat is trying to tell us. Sometimes it may simply be "Hey! My litterbox is stinky!" other times it may be a different cry for help. For more information, please read the 4 part series of blog articles that we have prepared on bladder and litterbox issues which begins here. 

Inflammatory Bowel Disease vs. Irritable Bowel Syndrome: Which is affecting my cat?

INFLAMMATORY BOWEL DISEASE

What is Inflammatory Bowel Disease and what causes it?

Inflammatory Bowel Disease (IBD) is a chronic disease of the intestinal tract. In fact, IBD is not a single disease, but several conditions that result in the accumulation of inflammatory cells in the intestinal tract. These inflammatory cells are normal cells that occur in the body, but problems within the body cause these cells to congregate in the stomach or intestinal tract, causing thickening of the linings of these organs and decreasing the organs' ability to perform their normal activities: digesting food and absorbing nutrients.The thickened lining also decreases the body's ability to protect itself from harmful invaders like bacteria and viruses. The lining of the intestinal tract normally functions similarly to the skin in providing a protective layer between harmful infections and the rest of the body's vulnerable cells.

Normal intestinal anatomy - the villi absorb nutrients and pass them into the bloodstream for distribution throughout the body

Most of the time, the primary cause of IBD is unknown or "idiopathic", but chronic inflammation may be caused by diet, environment, parasite infection, immune health or the relationship between the body's immune system and the bacteria that inhabit the digestive tract. While food allergy may not be a primary cause of  IBD, it may be a contributing factor to the severity of the disease.

What are the signs of Inflammatory Bowel Disease?

Inflammatory bowel disease is generally a problem found in cats of middle age and older, but can affect cats of any age. Most affected cats have a history of recurrent or chronic vomiting and/or diarrhea.  During periods of vomiting or diarrhea, the cat may lose weight but is generally normal in other ways. As a rule, most affected cats eat well (or even have an increased appetite) and appear normal, though some cats may have decreased appetite.

Depending on which part of the digestive tract is affected, the cat may be more likely to vomit (stomach, duodenum) or have diarrhea or bloody stools (colon). Mucousy stools may also be a sign of IBD. However, a cat that vomits due to IBD may vomit after every meal, or only once or twice a month. Vomiting may be intermittent or cyclical. The cat may be more prone to hairballs that disrupt the digestive tract - either vomiting hairballs frequently, or by having his digestive tract become obstructed by a hairball. If the whole digestive tract is affected, the symptoms may not necessarily directly correspond to the areas most affected.

How is IBD diagnosed?

Ultrasound examination of a cat

Diagnosis of IBD can be complex, because the common signs (vomiting and/or diarrhea) are symptoms that can be associated with many diseases. Because IBD often is idiopathic in nature, your veterinarian will recommend diagnostics that will rule out more specific diseases, first, such as parasites, viral or bacterial infections, metabolic diseases and cancer. This may involve various blood tests, a stool examination and abdominal radiographs or ultrasound examination. The veterinarian may palpate or feel thickened intestines during the physical exam, or may see evidence of intestinal thickening on x-ray or ultrasound studies.

For most cats with IBD, bloodwork chemistries may be normal. If the liver and pancreas are involved (triaditis), then elevations of pancreatic or liver enzymes would be expected. In cases where the cat is having bouts of severe vomiting or diarrhea, electrolyte imbalances would be a common finding. Additionally, long-standing IBD may result in "protein-losing enteropathy". In a normal cat, a small amount of protein leaks into the intestine as nutrients are absorbed into the bloodstream. These proteins are normally digested in the intestine and then reabsorbed. When the intestinal tract is damaged, as in IBD, more protein leaks out than the body is able to reabsorb.

The only way to definitively diagnose IBD is to collect surgical biopsies of the digestive tract and submit them for pathologist review. The types of cells seen by the pathologist will determine whether IBD is present, and categorize whether the IBD is lymphocytic-plasmacytic (the most common), eosinophilic, neutrophilic or granulomatous in nature. 

Here is what the lining of a normal intestine looks like under the microscope. The areas within the boxes are what we are looking at, below.

The images towards the left show normal intestinal anatomy, while the images to the right show progressively more severe Inflammatory Bowel Disease (human). There is a decrease in the size and surface area of the villi, the thickness of the intestinal lining , and a general degeneration of intestinal anatomy.  Loss of structure = loss of function

Surgical biopsies can be collected via endoscopy or via exploratory surgery. Endoscopic biopsies are less invasive, but are limited because only the upper end of the GI tract can be sampled, and only superficial samples can be collected. Surgical exploration to collect biopsy samples allows full-thickness biopsies of multiple sites throughout the digestive tract to be collected. Additionally, since many cats that have IBD may also have pancreatitis or hepatitis (inflammation in the pancreas or liver), samples of these organs and abdominal lymph nodes can also be collected to ensure that there are no additional complicating factors to the disease.

The first method is a biopsy of the affected part of the stomach or intestine.  The preferred technique to to use a flexible endoscope which allows access to the lining of the stomach, small intestine, and colon.  If the site of inflammation involves any of these locations, a confirmed diagnosis is achieved.  Sometimes, the small intestine may be difficult to enter because of the cat’s small size; in these cases, surgical biopsy may be needed.  Fortunately, this is rarely necessary. The second method of diagnosis is a therapeutic trial involving administration of particular drugs, along with certain dietary changes.  Since not all cats respond to the same drugs, the trial may involve a series of a number of drugs and may take several weeks.  Also, different diets may be tried, depending on which part of the bowel appears most involved.  These diets include hypoallergenic, low residue, or high fiber foods.  The cat is monitored during the therapeutic trial for a decrease in clinical signs and, in some cases, weight gain.

Is IBD treatable?

Treatment for IBD is focused on controlling symptoms such as vomiting and diarrhea and promoting appetite and weight gain. Any complicating factors such as pancreatitis, parasite infection or other diseases should be treated accordingly. Treatment may involve a special diet, anti-vomiting or anti-diarrheal medications, steroids, pre- or pro-biotics, dewormers, omega-3 fatty acids, and B12 supplementation.

What is the prognosis?

Once the appropriate drugs or diet are determined, many cats are maintained on these for life, although dosages of the drugs may eventually be decreased.  Occasionally, a cat will be able to stop drug therapy at some point. Most cats do well for many years; others require alterations in therapy every few months.  Unfortunately, a few cats will ultimately become totally resistant to treatment.

There is a correlation between IBD and gastrointestinal lymphoma in cats. It is not completely clear whether IBD causes or progresses to lymphoma (the most common type of cancer in cats) over time, or whether the same problems that lead to IBD also cause GI lymphoma. Either way, untreated IBD in cats can cause malnutrition and eventual gastrointestinal ulceration and possible perforation of the bowel. Perforation of the bowel allows partially digested food and intestinal bacteria to leak into the abdomen causing severe systemic infection, sepsis and death.

IBD vs. IBS

Irritable Bowel Syndrome (IBS) is not the same as Inflammatory Bowel Disease (IBD). Irritable bowel syndrome is a psychosomatic response that causes hypermotility in the intestinal tract (things move through too quickly). The most common reason for this to happen is excessive stress or anxiety - a trip to the veterinary hospital, the addition of a new cat or new baby to the household, etc. A biopsy of the intestinal tract would look normal, because the problem is not with the intestinal tract itself, but with the nerve signals sent to the intestine that tell it what to do. Treatment of chronic irritable bowel syndrome is aimed at increasing fiber in the diet and controlling the cat's anxiety through environmental management and behavioral therapy. One-time bouts of IBS resulting from travel, visits to the veterinary hospital or other planned events can be averted by acclimating the cat to the carrier, using calming products, such as Feliway or anti-anxiety medications prior to travel or veterinary visits, or by choosing a veterinary office that is a certified Cat Friendly Practice. These hospitals generally have staff experienced with handling stressed cats, have separate waiting rooms, cages and exam rooms for cats and dogs, and may be better equipped to soothe your anxious kitty, preventing the onset of an IBS episode.

Additional Resources
Merck Veterinary Manual: Disease Profile: Inflammatory Bowel Disease 

All Feline Hospital: Inflammatory Bowel Disease 

Cornell Feline Health Center: Inflammatory Bowel Disease

WebMD: Inflammatory Bowel Disease

Wild Rose Cat Clinic Case Study: Tigger, and is it IBD or Lymphoma?

World Journal of Gastroenterology: Inflammatory Bowel Disease in the Dog: Similarities and Differences with Humans

Does canned food cause diarrhea in cats?

A happy cat after having surgery to remove a piece of foam that was blocking his intestines

A very common thought among cat owners is that canned food causes diarrhea in cats. In fact, last Friday, one of our technicians had a conversation about that exact topic no less than three times!

1) Someone commented on a Facebook post with a question about her neighbor's cats. Her own cats thrive on a canned diet, but her neighbor objects, saying that it gives her cats diarrhea.

2) A woman brought in a kitten for a first visit that was having chronic soft stools and gas. She was concerned that the kitten was getting diarrhea from the canned food, but switching to a dry food did not significantly improve the problem.

3) At a dinner party, a friend leaned across the dinner table and said, "Not to be indelicate, but I'd like to pick your brain about my 3 year old cat's soft, smelly stools." His wife is concerned that canned food was the culprit, but the cat has been having diarrhea since they got her, and cutting out the canned food did not solve the problem. She has had her stool tested and she is up to date on vaccines. They had just moved to a new home and wondered how to approach a new veterinarian about the problem.

Most of the time, diarrhea in cats is not caused by eating canned food. Canned food is very close to what a cat would eat naturally, in the wild - the nutrient balance and moisture content of canned food is close to that of a mouse - and more natural than dry kibbles. It can be easy to blame diet for a cat's smelly, soft stools, but more often, we need to do some detective work to get to the root of the problem.

How do you diagnose the cause of diarrhea?

Usually, when presented with a cat that is having diarrhea, the veterinarian will recommend that the cat be checked for intestinal parasites. That is usually a very treatable reason to have chronic diarrhea. In Michigan, in Oakland County, in 2014, 1 in every 15 cats was positive for roundworms (compared to 1 in 46 dogs). It can also be a very difficult diagnosis to reach. When we test cats for intestinal parasites, the accuracy of the testing has a lot of contributing factors:

- the age of the stool sample. The older the sample, the less accurate the test. Usually a sample should be tested within 24 hours. Some parasites may be absent from the stool unless it is taken directly from the cat to the microscope! Tapeworms are mobile when they are deposited in the litterbox with your cat's stool, so they may wiggle off the stool before it is collected for testing. Tapeworms are more frequently diagnosed by observation of tapeworm segments on the hairs around the cat's anus than by bringing in a stool sample.

- the amount of stool. If a cat is having frequent, terrible diarrhea, it may be difficult to collect a sample, because only small amounts are produced very frequently.

- the life stage of the parasite. Some intestinal parasites do not shed eggs with every stool sample. When we look at a stool sample, we are most commonly looking for the eggs of the parasite, not the worm, itself. Other parasites are single-celled organisms and shed frequently, or their populations may wax and wane. Toxoplasmosis is an infection with a single-celled organism. Cats that are infected with this parasite will start shedding eggs (oocysts) in their stool  between 3-10 days after becoming infected and will only shed these oocysts for a total of 10-14 days. Ever. If you don't test a stool sample within that period, a stool sample will not diagnose this parasite. After that time frame, Toxoplasmosis infection must be diagnosed with blood titers that check for Toxoplasmosis antibodies.

For more information about cats and parasites, visit the Pets and Parasites website.

Sometimes, it may require that we test multiple stool samples before we are able to locate the parasite in the stool. One of our technicians had to check her cat three times before we were able to locate the Giardia that she was pretty sure was infecting her cat.

In cases where we suspect a difficult to diagnose parasite, or a viral or bacterial cause of diarrhea, we may recommend a "diarrhea panel". This test requires a larger stool sample and checks for two species of Campylobacter, Clostridium perfringens alpha toxin (CPA) gene, Cryptosporidium spp., feline coronavirus (FeCoV), feline panleukopenia virus, Giardia spp., Salmonella spp., Toxoplasma gondii, and Tritrichomonas foetus with PCR testing. A PCR test allows for certain types of DNA to be sorted out of a mixture of different types of DNA so that they can be identified. In this way, the laboratory can sort out the normal intestinal bacteria from bacteria that cause disease (are pathogenic), and find traces of parasites that may be present in small quantities, or identify viruses that may be present.

Hairballs can often be a culprit of intestinal maladies in cats. Sometimes, when the hair builds up in the system instead of passing normally, it can be a sign of a bigger issue - skin allergies or external parasites causing the cat to groom excessively, or decreased gut motility (the speed at which food moves through the digestive tract).

Another hairball - too large to pass through the stomach sphincter

Sometimes, a cat may have abnormal anatomy - here, the cat has a gastric diverticulum - a dead-end pouch off the stomach

This cat has a duodenal diverticulum - a dead-end pouch off the upper part of the small intestine

Sometimes, the intestinal problem is related to something the cat ate...anything from rubber bands, shoe strings and hair scrunchies to difficult to digest plant parts, to creepy, grinning toy parts...

Additional testing that might be recommended is highly dependent on the age of the cat, its unique symptoms, and the veterinarian's physical exam. It is highly likely that abdominal x-rays will be recommended. Special contrast studies may be recommended based on the results of the first films - for this, either barium or air will be introduced into the cat's intestinal tract for better imaging. Various blood tests may be recommended - from FeLV/FIV testing, to metabolic testing of kidneys, liver, glucose levels, thyroid levels, or pancreatic function testing.

 

What causes diarrhea in cats?

Sometimes, a cat may have a sensitive stomach that causes them to have diarrhea when their food is switched too rapidly. If they have eaten only dry food all their lives and are suddenly offered only canned food, in this case, canned food may cause diarrhea. However, if you transition food gradually, this should prevent diarrhea related to food transition. Cats may have a sensitivity to a certain protein in their diet. Very commonly, we hear of cats with beef sensitivities, though more in the context of vomiting versus diarrhea. (It make some sense, since we're pretty sure that domestic cats do not naturally hunt down cattle for dinner. Lions, yes. Fluffy, no.) It may be that a cat will have an intolerance to a particular brand of canned food, too, but rarely does canned food as a whole food group cause diarrhea. This would be similar to a human being unable to eat any type of soup or stew without digestive issues.


Besides intestinal parasites and food transitions, other problems that can cause diarrhea in cats include:
- viruses such as Distemper, Feline Leukemia, FIV, and Coronavirus/FIP
- toxin ingestion - plant or others
- Salmonella
- fungal infections
- body-system diseases including: kidney disease, hyperthyroid disease, pancreatitis, and diabetes
- cancer
- inflammatory diseases such as inflammatory bowel disease (IBD), fiber-responsive diarrhea, colitis
- pancreatic insufficiency
- foreign body ingestion (your cat ate a toy!) or other bowel obstruction (hairball, constipation)
- spoiled food
- certain medications (for example, some antibiotics are commonly known to cause diarrhea)

It may be yucky to look at, but using this chart to score your cat's stool can be very helpful!

What can I do to help the veterinarian diagnose my cat?

When trying to hunt down the cause of a complex diarrhea case, it may be helpful to keep a diary of what food you fed your cat each day and rate their stool consistency. We tend to sort cats' stools into the following categories:

- solid, normal stools - "Tootsie Rolls"
- soft stools with some form, but may appear to be "melting", also known as "soft serve stools"
- soft stools with little to no form - "pudding stools"
- liquid diarrhea, may be confused with urine in clumping litter, may be volatile, often the cat may be  unable to make it to the litterbox. This liquid may be brown in coloration or may be clear and difficult to distinguish from vomit.

Note any blood or mucus in the stool. Fresh red blood (frank blood) may be related to irritation of the intestinal tract or anus. Dark, tarry stools or blood that looks like coffee grounds contains older, clotted blood and is a more critical and severe concern than fresh blood. Mucous in the stool is often thick and clear and can be passed with the stool or separately. You may want to snap photos of the diarrhea to show your veterinarian. It can often be helpful, and we will never be offended. Note the frequency of the diarrhea and any other symptoms your cat may have.

When should you see the veterinarian?

Diarrhea is often considered to be a smelly nuisance, however, significant, chronic diarrhea can cause dehydration and malnutrition and can become a life threatening situation.

Contact your veterinarian right away if your cat’s diarrhea:

• is accompanied by repeated vomiting, lethargy, loss of appetite, abdominal pain, generalized weakness, or fever. Vomiting of a dark green liquid (bile) is commonly an indication of a complete intestinal blockage.
• contains large amounts of frank blood.
• is black or tarry in color.
• might be related to ingesting something toxic.
• occurs in a kitten under nine months of age, particularly if vaccines were missed.
• occurs in an elderly or medically frail animal.
• fails to respond or gets worse despite 48 hours of symptomatic home care.

Your cat wants to stop having diarrhea as much as you want him to!

 If you are new to an area and are not sure how to approach a new veterinarian with your problem, it may be best to simply collect a fresh stool sample and take it into the office. A stool sample can often be analyzed without first seeing a cat, though if medication needs to be dispensed, an exam will be necessary. This is because pharmacy laws in most states require an established doctor-patient relationship before any medication can legally be dispensed. If the parasite exam is negative, you will also need to bring your cat in for an exam and consultation about your cat's lifestyle and unique characteristics, so it may be best to contact the new veterinarian and schedule an appointment and bring a stool sample with you at the same time. Having your records sent from your old veterinary hospital to your new hospital will also be helpful, because it will give your new veterinarian an idea of your cat's past weight gains and losses, vaccine history, and any bloodwork or x-rays that have been done in the past.

Additional resources:
Pet Education: Diarrhea in cats: Causes, Diagnosis and Treatment
Cat Diarrhea Causes, Symptoms, Treatment and more